Endocrine Abstracts

Introduction: Pentraxin 3 (PTX3) is an acute-phase protein that shares structural homology with C-reactive protein (CRP). PTX3 is produced in macrophages, endothelial cells, and adipocytes in response to inflammatory stimuli, whereas hepatocytes are the main source of CRP. Because obesity and metabolic syndrome (MetS) are considered chronic inflammatory states, PTX3 might be involved in the pathogenesis of obesity and MetS as well as CRP. In this study, we aimed to investigate...

Introduction: Recent studies suggested that plasma levels of osteocalcin (OC) were negatively associated with both fat mass and plasma glucose. These findings may suggest that endocrine function of the osteoblast-derived osteocalcin on fat mass/glucose homeostasis in mice also might exist in humans. The aim of this study was to determine if osteocalcin has any effect on fat distrubution in different parts of body.Methods: Eighty-six obese premenapousal w...

Introduction: It has been demonstrated that there are differences in the effect of body mass index (BMI) on the serum 25-hydroxyvitamin D levels (25-OH D); differences appeared stronger in subjects with higher BMI. In this study we aimed to assess the association between 25-OH D status and body fat distribution and caratid intima medai thickness.Methods: 86 obese premenapousal women (aged 17–55 years) and 56 women with normal BMI took part in this s...